What's New

July 26, 2018 Our new review entitled “Targeting Myosin by Blebbistatin Derivatives: Optimization and Pharmacological Potential” has been published in Trends in Biochemical Sciences.

We constructed a SAR analysis based on blebbistatin derivatives and discuss the pharmacological perspectives of blebbistatin development. We also synthetize literature data on its characteristics and compare potentially useful alternatives, like para-nitroblebbistatin or para-aminoblebbistatin. The preprint is available here

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