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para-Nitroblebbistatin

June 20, 2014: Our new research article has been published in Angewandte Chemie

The online version of our new paper entitled ‘para-Nitroblebbistatin, the Non-Cytotoxic and Photostable Myosin II Inhibitor’ has been published in Angewandte Chemie International Edition. The study demonstrates the in vitro and in vivo characterization of a photostable, C15 nitro derivative of blebbistatin with improved biological features: it is neither photo- nor cytotoxic while exhibiting identical myosin II inhibitory properties. Képiró M&Várkuti BH et al. Angew Chem. 2014, 126.31: 8350-8354.

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